Detalhe da pesquisa
1.
Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution.
Cell
; 184(20): 5247-5260.e19, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34534445
2.
Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.
Cell
; 162(4): 738-50, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26276630
3.
Convergence of coronary artery disease genes onto endothelial cell programs.
Nature
; 626(8000): 799-807, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326615
4.
Genome-wide enhancer maps link risk variants to disease genes.
Nature
; 593(7858): 238-243, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33828297
5.
Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations.
Nature
; 559(7714): 350-355, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29995854
6.
Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.
Hum Mol Genet
; 30(16): 1521-1534, 2021 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33987664
7.
Estimating cross-population genetic correlations of causal effect sizes.
Genet Epidemiol
; 43(2): 180-188, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30474154
8.
Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues.
Am J Hum Genet
; 100(4): 605-616, 2017 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28343628
9.
Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates.
Am J Hum Genet
; 97(6): 775-89, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26581902
10.
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Am J Hum Genet
; 97(4): 576-92, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26430803
11.
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.
Bioinformatics
; 33(2): 272-279, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27663502
12.
Improving fine-mapping by modeling infinitesimal effects.
Nat Genet
; 56(1): 162-169, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036779
13.
Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
medRxiv
; 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333223
14.
Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
Nat Commun
; 14(1): 7659, 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036535
15.
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.
Nat Genet
; 55(8): 1267-1276, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37443254
16.
An encyclopedia of enhancer-gene regulatory interactions in the human genome.
bioRxiv
; 2023 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014075
17.
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution.
Cell Genom
; 2(12)2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36643910
18.
Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways.
Sci Adv
; 8(16): eabl4602, 2022 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452290
19.
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores.
Nat Genet
; 54(4): 450-458, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393596
20.
Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs.
Nat Commun
; 12(1): 3394, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099641